Robert J. Gallagher has been a member of our board of directors since March 2002. Mr. Gallagher has been retired since December 2000. Mr. Gallagher served as interim President and Chief Operating Officer of Acuson, an ultrasound company, from February 2000 to December 2000. From 1997 to 1999, Mr. Gallagher served as Acuson's Chief Operating Officer and Vice-Chairman of the board of directors, and as Acuson's President and Chief Operating Officer and a member of the board of directors from 1995 to 1997. Mr. Gallagher joined Acuson in 1983 as Vice President of Finance and Chief Financial Officer. Mr. Gallagher holds an M.B.A. from Stanford University and a B.S. degree in electrical engineering from Rutgers University.

Christopher Hollowood has served on our board of directors since June 2009. Currently, Mr. Hollowood is a principal with Apposite Capital LLP. Mr. Hollowood started his investment career as a fund manager with Neptune Management, with responsibility for Healthcare sector investments, before moving into Healthcare focused venture capital and corporate advisory at Bioscience Managers. He attained his first degree in Natural Sciences, specializing in Chemistry, and a PhD in Organic Chemistry, both from Cambridge University. Between his first and second degree, Chris worked in the pharmaceutical industry as a medicinal chemist at GlaxoWellcome (GlaxoSmithKline) and Pfizer.

Nader J. Naini has served on our board of directors since October 2001. Mr. Naini joined Frazier Healthcare Ventures, a venture capital firm, shortly after its inception in 1991 and has been a General Partner and served on the firm's management committee since 1995. Prior to joining Frazier Healthcare, Mr. Naini was with Goldman Sachs & Co. Mr. Naini holds an M.B.A. from the Leonard N. Stern School of Business at New York University and a B.A. in molecular biology from the University of Pennsylvania.

Thom E. Rasche has been a member of our board of directors since April 2004. Since January 2007, Mr. Rasche has been a partner at Earlybird Venture Capital, a venture capital firm, where he previously served as a Venture Partner from July 2003 to December 2006. Prior to joining Earlybird, Mr. Rasche was the Managing Director for ETHICON Endo-Surgery, a division of ETHICON GmbH (a Johnson & Johnson company), from January 2000 to June 2003. Mr. Rasche holds a Degree as Diplom Kaufmann (M.B.A. equivalent) from the University of Applied Sciences in Lüneburg, Germany, specializing in Marketing and Human Resource Management.

Joseph E. Whitters has served on our board of directors since January 2007. Since October 2005, Mr. Whitters has been a senior advisor to Frazier Healthcare Ventures. From October 1986 to January 2005, Mr. Whitters was with First Health Group Corp., or First Health, a managed healthcare company, where he held various financial positions and served as Chief Financial Officer from 1988 to 2004. First Health was sold to Coventry Health Care, Inc., a managed health care company, in 2005. Mr. Whitters currently serves as the Chairman of the Board of Mentor Corporation, a provider of products serving the aesthetic medicine market and as a director of Omnicell, Inc., a provider of systems and software solutions targeting patient safety and operational efficiency in healthcare facilities, and Luminent Mortgage Capital Inc., a real estate investment trust. Mr. Whitters holds a B.A. in accounting from Luther College.